Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R*,R*)-

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Names and Identifiers

Name	Formoterol
Synonyms	Formoterol Eformoterol FormoterolBase FORMOTEROL TARTARATE n-[2-hydroxy-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide N-[2-Hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]- Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)-(+-)- Formamide, N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, rel-
CAS	73573-87-2
InChI	InChI=1/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22)

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Physico-chemical Properties

Molecular Formula	C19H24N2O4
Molar Mass	344.4
Density	1.233±0.06 g/cm3(Predicted)
Boling Point	603.2±55.0 °C(Predicted)
Flash Point	318.6°C
Solubility	DMSO: 20mg/mL, soluble
Vapor Presure	2.12E-15mmHg at 25°C
Appearance	solid
Color	off-white
pKa	8.95±0.50(Predicted)
Stability	Stable. Incompatible with strong oxidizing agents.
Refractive Index	1.616

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Risk and Safety

WGK Germany

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Preparation Method

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M-Nitro methyl paraben and benzyl chloride reaction, the resulting compound dissolved in chloroform, Dropwise into bromine reaction, reaction recrystallization treatment, the obtained compound and n-benzyl-1-p-methoxyphenyl-2-propylamine were refluxed in methyl ethyl ketone, the precipitate was removed by filtration, the filtrate was concentrated under reduced pressure, and the obtained substance was recrystallized from ethanol, the obtained compound was further reacted with sodium borohydride in ethanol, the solvent was distilled off under reduced pressure, and the remaining solution was extracted with benzene. After washing with water and drying, the obtained product is mixed with hydrochloric acid and methanol, iron powder is added to the reaction under stirring, the black precipitate is removed by filtration, the filtrate is further treated, and the obtained compound is in chloroform, formic acid-acetic anhydride mixture was added and the reaction was stirred. The obtained material was reacted together with Isopropanol (or ethanol) and palladium-carbon catalyst, filtered and concentrated to obtain crude formoterol. The crude product was converted to crystalline fumarate by treatment.

Last Update：2024-01-02 23:10:35

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Use

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Japan within the mountains Development, March 1986 for the first time on the market. Long-acting, selective beta 2-receptor agonists, strong bronchodilating effect, as well as anti-allergic and edema-inhibiting effect. For the relief of bronchial asthma, acute and chronic bronchitis, asthmatic bronchitis and emphysema caused by Dyspnea and other symptoms.

Last Update：2022-01-01 09:09:54

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Safety

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LD50 male and female mice, male and female rats (mg/kg): 6700, 8310, 3130, 5580 orally; 72,71,98,100 intravenously, 240,210, 170,210 intraperitoneal injection; 640, 670, 1100, subcutaneous injection.

Last Update：2022-01-01 09:09:55

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R*,R*)-

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Hubei YoungXin Pharmaceutical Tech Co.,Ltd.

Spot supply

Product Name: Formoterol Visit Supplier Webpage Request for quotation
CAS: 73573-87-2
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052

Wechat: 15671228036

Hubei Yangxin Medical Technology Co. LTD

Product Name: Formoterol Request for quotation
CAS: 73573-87-2
Tel: 0714-3999001
Email: 3003392093@qq.com
Mobile: 15374527030
QQ: 3003392093

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Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R*,R*)-

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)-

Formoterol

CAS: 73573-87-2

Molecular Formula: C19H24N2O4

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Names and Identifiers

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Physico-chemical Properties

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Risk and Safety

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Preparation Method

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Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Use

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Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Safety

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Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R*,R*)- Request for Quotation

Formoterol

CAS: 73573-87-2

Molecular Formula: C19H24N2O4

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R*,R*)- - Names and Identifiers

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R*,R*)- - Physico-chemical Properties

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R*,R*)- - Risk and Safety

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R*,R*)- - Preparation Method

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Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R*,R*)- - Use

Open Data Verified Data

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R*,R*)- - Safety

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Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)-

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Names and Identifiers

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Physico-chemical Properties

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Risk and Safety

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Preparation Method

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Use

Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (R,R)- - Safety